Muscle cells have the incredible ability to convert the chemical energy of adenosine triphosphate (ATP) into the mechanical energy of muscle contraction.
There are three main events that need to take place to allow contraction of skeletal muscle fiber:
Electrical excitation of a muscle fiber
Muscle fiber contraction due to the sliding filament mechanism
Read and watch the following animation below to evaluate and interpret the process involved in the activation of the actin-myosin cross bridge (sliding filament mechanism) in skeletal muscle contraction.
Electrical Excitation of a Muscle Fiber
Skeletal muscle fiber cells can be stimulated by a somatic motor neuron resulting in depolarization of the sarcolemma. If this depolarization reaches threshold, an action potential is initiated resulting in muscle contraction.
Describe a somatic motor neuron and how it communicates with a skeletal muscle cell?
Describe the process of depolarization within the sarcolemma and what is required for a stimulus to reach threshold, resulting in skeletal muscle contraction?
An action potential is transmitted along the sarcolemma and down the T tubules (transverse tubules). This action causes calcium ions to be released from the terminal cisternae of the sarcoplasmic reticulum. Calcium ions couple electrical excitation to muscle fiber contraction by binding to troponin.
Two events happen when calcium binds to troponin.
Describe these two events in great detail.
Muscle Fiber Contraction due to the Sliding Filament Mechanism
Watch the animated interaction between actin and myosin in the sliding filament mechanism during skeletal muscle contraction. https://www.youtube.com/watch?v=hgLSLJ09fZM
Evaluate and interpret the process in the actin-myosin cross bridge (sliding filament mechanism) during skeletal muscle contraction and answer the following questions below:
What happens to the position of the myosin head when ATP is hydrolyzed and ADP is attached to the myosin head group?
What event happens immediately after the myosin head binds to the active site on actin? Describe this process in great detail.
What happens to the position of the myosin head when ATP binds to the myosin head group?
Why does the actin filament only move in one direction? Describe in great detail.
At Solution Essays, we are determined to deliver high-quality papers to our clients at a fair price. To ensure this happens effectively, we have developed 5 beneficial guarantees. This guarantees will ensure you enjoy using our website which is secure and easy to use.
Most companies do not offer a money-back guarantee but with Solution Essays, it’s either a quality paper or your money back. Our customers are assured of high-quality papers and thus there are very rare cases of refund requests due to quality concern.Read more
All our papers are written from scratch and according to your specific paper instructions. This minimizes any chance of plagiarism. The papers are also passed through a plagiarism-detecting software thus ruling out any chance of plagiarism.Read more
We offer free revisions in all orders delivered as long as there is no alteration in the initial order instruction. We will revise your paper until you are fully satisfied with the order delivered to you.Read more
All data on our website is stored as per international data protection rules. This ensures that any personal data you share with us is stored safely. We never share your personal data with third parties without your consent.Read more